An agreement is in place for the 23-year-old to move to Old Trafford for around £40 million.
United are set to discuss personal terms with Van de Beek before the Netherlands international undergoes a medical ahead of the transfer.
United manager Ole Gunnar Solskjaer has tracked Van de Beek for more than a year with the club making an enquiry about his availability in January before signing Bruno Fernandes.
Solskjaer and the club see a deal for Van de Beek as a good opportunity to strengthen the squad in a window during which they have struggled to agree a fee with Borussia Dortmund for Jadon Sancho. At around £40m, van de Beek is seen as reasonably priced while at 23, he also fits into the right age bracket for Solskjaer's rebuild.
He had been linked with a move to Barcelona in recent weeks to link up with his former national team coach Ronald Koeman.